邮箱：kqguoyaru@bjmu.edu.cn

        地址：北京市海淀区中关村南大街22号

 个人简介 

郭亚茹，北京大学口腔医院副研究员/助理教授，博士生导师，近年来紧密围绕“口腔颌面部组织再生与材料研发”展开科学研究，取得重要研究成果。在国际著名学术期刊上以第一作者（含共同）发表SCI论文17篇，包括Advanced Materials (2024, 2025)、Matter (2025)、Advanced Functional Materials (2025, 2021)、Bioactive materials (2022, 2024)、Bone Research (2024)等，入选中国科协青年托举人才工程，主持国家重点研发计划子课题等国家级项目5项，授权国际专利1项、国家发明专利6项。获评北京大学医学部博雅博士后和优秀博士后称号，获中华口腔医学会口腔科研管理分会青年科学家报告会“一等报告”、中华医学科技奖一等奖（6/10）、教育部科技奖一等奖（11/17）、中华口腔医学会科技奖一等奖（9/13）。

        

 主要研究方向 

                1、口腔颌面部血管再生机制

                2、口腔颌面部修复材料研发

 代表性科研项目 

1、中国科协，中国科协青年人才托举工程，2024QNRC001，面向颅颌面血管化再生的材料体系研发，2024.10至2026.12，30万元。

2、国家自然科学基金，国家自然科学基金青年项目，82201123，电学微环境调控尖端细胞和茎细胞分化，2023年-01至2025-12，30万。

3、中国生物技术发展中心，国家重点研发计划课题二子课题，2022FYC2405902，龋病预防和治疗矿化材料研发，2022-11至2027-10，15万元。

4、中国博士后科学基金会,中国博士后科学基金第16批特别资助，2023T160029，学微环境在尖端细胞分化中的作用，2023-09至2025-09，18万元，在研，主持。

 代表性论文 

1. Yaru Guo#, Shuai Ding#, Changshuai Shang#, Chenguang Zhang, Menggang Li, Qinghua Zhang, Lin Gu, Boon Chin Heng, Shihan Zhang, Feng Mei, Ying Huang, Xuehui Zhang, Jiuhui Jiang*, Shaojun Guo*, Xuliang Deng* and Lili Chen*, Multifunctional PtCuTe nanosheets with strong ROS scavenging and ROS-independent antibacterial properties promote diabetic wound healing, Advanced Materials. 2024, 36(8): 2306292.

2. Xiaowen Sun#, Yaru Guo#, Xiaona Zheng#, Yunyang Bai#, Yixuan Lu, Xue Yang, Ziming Cai, Erxiang Xu, Ying He, Boon Chin Heng, Mingming Xu, Xuliang Deng, and Xuehui Zhang*, Optimizing the electrical microenvironment provided by 3D micropillar topography on a piezoelectric BaTiO3 substrate to enhance osseointegration, Advanced Materials. 2025, 37(4), 2414161.

3. Yaru Guo#, Siqin Ma#, Mingming Xu#, Yan wei, Xuehui Zhang, Ying huang, Ying He, Boon Chin Heng, Lili Chen* and Xuliang Deng*; HtrA3-mediated endothelial cell-extracellular matrix crosstalk regulates tip cell specification, Advanced Functional Materials. 2021, 31(30): 2100633.

4. Yaru Guo, Feng Mei, Ying Huang, Siqin Ma, Yan Wei, Xuehui Zhang, Mingming Xu, Ying He, Boon Chin Heng, Lili Chen* and Xuliang Deng*; Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-Yap signaling axis; Bioactive Materials. 2022, 7: 364-376.

5. Yaru Guo#, Siqin Ma#, Dandan Wang#, Feng Mei#, Yusi Guo#, Boon Chin Heng, Sihan Zhang, Ying Huang, Yan Wei, Ying He, Wenwen Liu, Mingming Xu, Xuehui Zhang*, Lili Chen*, Xuliang Deng*, HtrA3 paves the way for MSC migration and promotes osteogenesis, Bioactive Materials. 2024, 38: 399-410. (IF: 18.0)

6. Youxing Liu#, Yaru Guo#, Nadaraj Sathishkumar, Minghui Liu, Lu Li, Zhiyuan Sang, Rongjuan Feng, Zongqiang Sun, Chenglong Sun, Mingchuan Luo, Xuliang Deng, Gang Lu*, Shaojun Guo*, Halogen Atom Induced Local Asymmetric Electron in Covalent Organic Frameworks Boosts Photosynthesis of Hydrogen Peroxide from Water and Air, Matter, 2025, 8(5): 1-11.

7. Yusi Guo#, Yijun Wang#, Yaru Guo#, Xiaohan Dai#, Yang Shen, Minzheng Yang, Houbing Huang, Dingxin Wang, Qun Cui, Xiaona Zheng, Jia Song, Yanhui Lu, Xuehui Zhang*, NIR-manipulated Pyroelectric PDA@BTO/P(VDF-Trfe) Membrane for Macrophage Reprogramming and Bone Regeneration, Advanced Functional Materials. 2021, 31(30): 2100633.

8. Dandan Wang#, Yaru Guo#, Boon chin Heng, Xuehui Zhang, Yan Wei, Ying He, Mingming Xu, Bin Xia*, and Xuliang Deng*, Cell membrane vesicles derived from hBMSCs and hUVECs enhance bone regeneration, Bone Research, 2024, 12(23): 1-11.

9. Yanhui Lu#, Yanze Meng#, Hui Li#, Yunyang Bai#, Ying He#, Boon Chin Heng, Yating Song, Xiaoyu Han, Yifei Zhang, Youde Liang, Lei Zhang, Yaojin Wang*, Yaru Guo*, Mingming Xu*, Xuliang Deng, Xuehui Zhang*, Self-Bactericidal and Long-Lasting Resin Nanocomposites with Pyrocatalytic Activity Regulated by Oral Temperature Fluctuation, ACS Applied Materials & Interface, 2025.

Yu Wang#, Shanshan Jin#, Yaru Guo#, Yilong Lu, Jingya Hou, Xuliang Deng, Adhesive and injectable hydrogel microspheres for NRF2-mediated periodontal bone regeneration, International Journal of Oral Science, 2025,17(1):7.